Analysis Of Strain Myocardial Associated With The Exercise Tolerance In Patients With Heart Failure Systolic
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Failure
- Sponsor
- Daniella Cunha Brandao
- Enrollment
- 26
- Locations
- 1
- Primary Endpoint
- Echocardiography for obtaining the "strain "
- Last Updated
- 9 years ago
Overview
Brief Summary
Introduction : Patients with heart failure (HF ) with systolic dysfunction of moderate to severe exhibit significant reduction in the ability to exercise compared to those with mild dysfunction , and have worse prognosis. However, some clinical markers of severity and diagnosis widely used in this population such as ejection fraction (EF) , are not always able to translate the actual degree of cardiac damage as well as their relationship with the cardiorespiratory fitness of these individuals and prognosis .
Objective: To evaluate the ability of the global longitudinal strain ( GLS ) in predicting exercise tolerance in heart failure patients with moderate and significant systolic dysfunction.
Investigators
Daniella Cunha Brandao
PhD
Universidade Federal de Pernambuco
Eligibility Criteria
Inclusion Criteria
- •moderate and significant systolic dysfunction (LVEF \< 45%) assessed by transthoracic echocardiography recent ( last month before evaluation ) Teichholz method , or when in the presence of contractile deficit target , by the Simpson method.
Exclusion Criteria
- •deformity in the face to prevent the coupling of the mask to perform the CPET ,
- •orthopedic and neurological diseases that could make it impossible to perform the tests ,
- •patients with psychiatric disorders that restricted them to respond to the questionnaire ,
- •HF FC IV or hospitalization in the last three months ,
- •angina unstable;
- •myocardial infarction or heart surgery up to three months before the survey ;
- •FEV1 / FVC \<70 % predicted characterizing obstructive respiratory disorder .
Outcomes
Primary Outcomes
Echocardiography for obtaining the "strain "
Time Frame: 1 day
To strain of technical analysis will be used echocardiography analysis software ( EchoPAC , GE Medical Systems, Horten , Norway, version 10.0 ) . The images will be analyzed in the longitudinal sections ( 4 bedrooms , 3 bedrooms and 2 cameras) . The endocardium is drawn manually from the septum to the lateral mitral annulus. A region of interest will be applied automatically by the software.
Secondary Outcomes
- Cardiopulmonary Test(1 day)