Analysis Of Strain Myocardial Associated With The Exercise Tolerance In Patients With Heart Failure Systolic
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Echocardiography for obtaining the "strain "
研究概览
简要总结
Introduction : Patients with heart failure (HF ) with systolic dysfunction of moderate to severe exhibit significant reduction in the ability to exercise compared to those with mild dysfunction , and have worse prognosis. However, some clinical markers of severity and diagnosis widely used in this population such as ejection fraction (EF) , are not always able to translate the actual degree of cardiac damage as well as their relationship with the cardiorespiratory fitness of these individuals and prognosis .
Objective: To evaluate the ability of the global longitudinal strain ( GLS ) in predicting exercise tolerance in heart failure patients with moderate and significant systolic dysfunction.
研究设计
- 研究类型
- Observational
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •moderate and significant systolic dysfunction (LVEF < 45%) assessed by transthoracic echocardiography recent ( last month before evaluation ) Teichholz method , or when in the presence of contractile deficit target , by the Simpson method.
排除标准
- •deformity in the face to prevent the coupling of the mask to perform the CPET ,
- •orthopedic and neurological diseases that could make it impossible to perform the tests ,
- •patients with psychiatric disorders that restricted them to respond to the questionnaire ,
- •HF FC IV or hospitalization in the last three months ,
- •angina unstable;
- •myocardial infarction or heart surgery up to three months before the survey ;
- •FEV1 / FVC <70 % predicted characterizing obstructive respiratory disorder .
结局指标
主要结局
Echocardiography for obtaining the "strain "
时间窗: 1 day
To strain of technical analysis will be used echocardiography analysis software ( EchoPAC , GE Medical Systems, Horten , Norway, version 10.0 ) . The images will be analyzed in the longitudinal sections ( 4 bedrooms , 3 bedrooms and 2 cameras) . The endocardium is drawn manually from the septum to the lateral mitral annulus. A region of interest will be applied automatically by the software.
次要结局
- Cardiopulmonary Test(1 day)
研究者
Daniella Cunha Brandao
PhD
Universidade Federal de Pernambuco