Comparison of perioperatively measured echocardiographic parameters describing the left ventricular function in patients undergoing minimal invasive surgical aortic valve replacement

Recruiting

• Conditions: I35; Nonrheumatic aortic valve disorders

• Registration Number: DRKS00032060
• Lead Sponsor: Herzzentrum Dresden Universitätsklinikum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

severe aortic stenosis
- elective minimal invasive OP (MIC LAT S technique)
- normal preoperative EF (>=50%)
- normal sinus rhythm
- written informed consent to participate

Exclusion Criteria

- rhythm other than sinus at T1 or T2
- hemodynamically relevant aortic insufficiency
- hemodynamically relevant mitral stenosis or insufficiency
- anatomically bicuspid aortic valve
- redo surgery

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparability of parameters quantifying the LV function (EF, Strain, Twist and Torsion) in the echocardiographic examination at T1 (intraoperatively, before incision) and T2 (intraoperatively, with valve prosthesis, short before the end of the surgery)

Secondary Outcome Measures

Name	Time	Method
time to discharge from ICU<br>time to discharge<br>cumulative dosis of catecholamines<br>time to extubation<br>rate of Major Adverse Cardiac Events<br>30-days and 1-year mortality