Effects of Functional Electrical Stimulation Cycling Versus Cycling Only on Walking Performance and Quality of Life in Individuals With Multiple Sclerosis: A Pilot Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Stony Brook University
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Gait Velocity: Timed Walking
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This study will seek to determine the benefits that FES-LE cycling has over cycling alone on walking performance and quality of life in people with multiple sclerosis.
Detailed Description
Functional Electrical Stimulation (FES) is a rehabilitation tool that stimulates nerves via electrical current, causing muscles to contract. When FES is appled to leg muscles during stationary cycling the legs move in a fixed rhythmical pattern. Previous studies have demonstrated that FES during cycling is a safe and effective exercise for individuals recovering from spinal cord injury or stroke, but few have applied this tool to a progressive disorder, such as multiple sclerosis (MS). The aim of this study is to assess the immediate and short-term effect of an 8-week training program comparing FES lower extremity cycling to cycling without FES. Twenty volunteers with MS will participate. They will be randomly assigned to a training group. This study examine the effects of training on quality of life, endurance, walking speed, and step quality. Participants will sign an informed consent and complete a questionnaire that includes medical history and demographic data. Before training, immediately after training finishes and one month after training, self-report questionnaires, timed walking tests will be completed. During the walking tests, step quality and speed will be measured with a sensor that is worn on a belt
Investigators
Lori Hochman
Clinical Assistant Professor
Stony Brook University
Eligibility Criteria
Inclusion Criteria
- •Medical Diagnosis of MS
- •Patient-determined Disease Steps score between 3.0 and 6.0 inclusive
- •Ability to attend training sessions 3 times per week for an 8-10 week period
- •Passing a submaximal exercise test
- •Adequate hip range of motion (at least 110 degrees)
- •Adequate knee range of motion (10-90 degrees)
Exclusion Criteria
- •Cognitive deficits that would interfere in ability to sign consent and understand the procedures for the study.
- •History or presence of other neurological pathologies that interfere with movement
- •Received physical therapy within the last 4 weeks prior to the study
- •History of an acute exacerbation of their MS symptoms within 4 weeks prior to the study
- •Immunosuppressive or steroid therapy within the past 4 weeks
- •Significant spasticity in the legs that interferes with the cycling motion
- •History of congestive heart failure
- •Coronary Artery Disease
- •Uncontrolled Hypertension
- •History of epilepsy or seizures
Outcomes
Primary Outcomes
Gait Velocity: Timed Walking
Time Frame: 12 weeks
Gait velocity was reported in meters/second based on a 25 foot walk test called the Timed 25 foot Walk Test. Faster gait speeds are better outcomes.
Secondary Outcomes
- Overall Self-reported Quality of Life Using Multiple Sclerosis Quality of Life- 54(8 weeks)
- Self-reported Fatigue Using Modified Fatigue Impact Scale(8 weeks)
- Self-reported Walking Using 12 Item Multiple Sclerosis Walking Scale(8 weeks)