Functional outcome one year after osteoporotic vertebral compression fractures

• Conditions: osteoporosis; vertebral fracture; 10017322; 10009720

• Registration Number: NL-OMON42227
• Lead Sponsor: Diakonessenhuis Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 110

Inclusion Criteria

male and female patients aged 50 years or older, fracture of the thoracal resp lumbal spine, fracture less than one week old, low-energy trauma, signed informed consent

Exclusion Criteria

neurologic deficit, active cancer, psychiatric or mental disease, insufficient cognitive or language skills to complete questionnaires

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint is the functional outcome one year after an OVCF,<br /><br>measured by pain level and quality of life. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Sagittale balance, measured on X-rays of total spine<br /><br><br /><br>Mineral bone density will be measured by DXA (mg per cm2, T-score) and finite<br /><br>element analysis of quantitative CT scans will be conducted to measure<br /><br>volumetric BMD (mg per m3).<br /><br><br /><br>Quality of life after three and six months<br /><br><br /><br>Physical activity, Accelerometer-based measurements of movement</p><br>