COMPARATIVE EVALUATION OF AQUEOUS BASED AND OIL BASED 0.05% CYCLOSPORINE EYE DROPS IN THE TREATMENT OF MODERATE TO SEVERE DRY EYE DISEASE

AIIMS NEW DELHI0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年2月21日

试验速览

暂无简介。

•1)Aged 18 to 65 years old
•2)Moderate to severe DED
•3)Tear film break-up time (TBUT) <= 10seconds
•4)Corneal fluorescein staining (fluorescein staining score of >3 out of 15 in either eye)
•5)Schirmer I test <= 5mm/5min
•6)OSDI score > 23

•1)History of ocular trauma,active blepharitis, infection, or inflammation not associated with DED during the 3-month period preceding the screening visit
•2)Patients with one blind eye
•3)Patients with history of active stage of any other concomitant ocular disease
•4)Ocular surgery within 3 months preceding the study
•5)History of hypersensitivity or any medical condition that contraindicates the use of the study drug or any of its compounds, or derivatives
•6)Patients taking any medication, topically or by any other route, which could interfere with the studyâ??s results, in the 3 days prior to trial, or until a time period in which residual effects could be present
•7)Contact lens wearer
•8)Fertile-age women with an inadequate birth-control method, as well as pregnant or breastfeeding women
•9)Legally disqualified or mentally disabled patients who cannot sign an informed consent
•10)Patients who cannot comply with medical appointments or with all protocol requirements
•11)Patients who disagree to participate in the trial

发起方

AIIMS NEW DELHI