The evaluation of effectiveness of Adjunctive use of sertraline on seizure improvement in patients with drug-resistant temporal lobe epilepsy

Shiraz University of Medical Sciences0 个研究点目标入组 30 人开始时间: 待定最近更新: 2022年3月8日

试验速览

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•Male / female (non-pregnant female adequately protected from conception) patients, between ages 18 and 65 years
•Patients with diagnosis of temporal lobe epilepsy
•The patient made on the basis of clinical findings with drug-resistant seizures defined as failure of two or more AEDs at maximal tolerated doses and one or more seizures per month
•The patients have stable medication regimen for four weeks prior to entry

•Patients with progressive neurological conditions
•Patients with a history of non adherence for seizure diary completion or frequent clinic visits
•Patients with a history of having any serious medical illness or major psychiatric disorder,
•History of psychogenic nonepileptic seizures
•History of suicidal attempt in the past five years any known
•Pracense of contraindication for sertraline administration including: concomitant use in patients taking monoamine oxidase inhibitors (MAOIs) and hypersensitivity to sertraline
•Taking any other medication with significant drug interaction with sertraline

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