The Efficacy and Treatment Mechanisms of the Web-based Acceptance and Commitment Therapy for Patients with Major Depressive Disorder
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Major Depressive Disorder
- Sponsor
- Gachon University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Acceptance and Action Questionnaire-II
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
PROSPECTIVE INTERVENTION STUDY; EFFICACY OF WEB-BASED ACCEPTANCE AND COMMITMENT THERAPY
Detailed Description
Acceptance Commitment Therapy (ACT) is known to help people recover from depression by improving psychological flexibility through acceptance, defusion, self-as-context, present moment, committed action, and helping them live a values-based life. This study is a randomized controlled trial to determine if web-based ACT leads to changes in the psychological flexibility and cognitive fusion. Also, through the functional MRI study, possible treatment mechanisms by which the web-based ACT exerts will be identified.
Investigators
Kyoung-Sae Na
Associate Professor
Gachon University
Eligibility Criteria
Inclusion Criteria
- •Patients who diagnosed major depressive disorder
Exclusion Criteria
- •Patients who have serious medical problems, metal implants in their bodies, severe brain injury or brain disease
- •Women who were pregnant or nursing
- •Patients at high risk for suicide
Outcomes
Primary Outcomes
Acceptance and Action Questionnaire-II
Time Frame: 6 weeks
Psychological flexibility
Hamilton Rating Scale for Depression
Time Frame: 6 weeks
Interviewer-rated depression scale
Secondary Outcomes
- Cognitive Fusion Questionnaire(6 weeks)
- Functional Connectivity(6 weeks)
- Valuing(6 weeks)
- Beck Depression Inventory(6 weeks)
- Beck Anxiety Inventory(6 weeks)
- Beck Hopelessness Scale(6 weeks)
- Beck Scale for Suicide Ideation(6 weeks)