New Modality for Post Covid Syndrome Patients

Not Applicable

• Conditions: Post Covid Syndrome

• Registration Number: NCT05271500
• Lead Sponsor: Cairo University

Brief Summary

Coronavirus (19) is a pandemic that affects many countries allover the world. Many patients experienced symptoms as dyspnea and fatigue after their recovery from coronavirus . These symptoms appear to occur regardless the severity of the infection. In addition, many studies reported change in the inflammatory status and immunity in post covid patients. laser acupuncture is a painless noninvasive modality that is used in treating many diseases. laser acupuncture appear to have a role in relieving symptoms, altering inflammatory status and boosting immunity in post covid patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-03
• Study First Submitted: 2022-03-07
• Study First Submitted QC: 2022-03-07
• Last Update Submitted: 2022-03-07
• Study First Posted: 2022-03-09
• Last Update Posted: 2022-03-09
• Study Start: 2022-03-15
• Primary Completion: 2022-06-30
• Study Completion: 2022-07-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• age will be ranged from 30 to 40 years
• patients were diagnosed as covid 19 by polymerase chain reaction test using nasopharyngeal swap
• patients will be negative polymerase chain reaction test (pcr) with symptoms of dyspnea and fatigue.
• patients will be recruited after 2 weeks post the negative pcr
• patients who want to participate and complete the study till the end

Exclusion Criteria

• patients with photosensitivity
• pacemaker plantation pregnant women
• BMI more than 30kg/m2 infection or inflammation at the site of acupuncture laser malignancy uncontrolled diabetes psychiatric disorders or mental retardation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
change in the level of CD 3 T cells	after 12 weeks of treatment	5ml of blood will be drawn and serum will be separated. cd3 level will be measured using BD FACS Canto flow cytometer
change in level of interleukin 4	after 12 weeks of treatment	BD FACS Canto flow cytometer with BD CBA human th1/th2 cytokine kit will be used
change in level of interleukin 6	after 12 weeks of treatment	BD FACS Canto flow cytometer with BD CBA human th1/th2 cytokine kit will be used
change in the level of cd4 T cells	after 12 weeks of treatment	cd4 will be measured using BD FACS Canto flow cytometer after blood sample will be separated
change in lymphocyte count	after 12 weeks of treatment	BD FACS Canto flow cytometer will be used
change in level of dyspnea	after 12 weeks of treatment	mMRC scale is a five point scale to detect degree of dyspnea while performing physical activity. it is ranged from 0-4

Secondary Outcome Measures

Name	Time	Method
change in fatigability	after 12 weeks of treatment	chalder fatigue scale is 11 items scale. people of 4 or more are considered meeting the criteria of fatigue