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临床试验/NCT04350255
NCT04350255
招募中
不适用

STEISURE - Trident II - A Registerbased Multicentric Prospective Study

Sahlgrenska University Hospital, Sweden1 个研究点 分布在 1 个国家目标入组 500 人2020年8月1日
适应症Prospective

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Prospective
发起方
Sahlgrenska University Hospital, Sweden
入组人数
500
试验地点
1
主要终点
Implant survival at 3 years
状态
招募中
最后更新
3年前

概览

简要总结

In a prospective register-based study, we aim to evaluate the implant survival, clinical outcomes and X-ray findings by following a cohort of patients operated with the Trident II cup.

详细描述

Data will be collected from a cohort consisting of minimum 500 total hip arthroplasties. The patients will be recruited from multiple high volume centers in Sweden. To determine if there is evidence of inferiority as per benchmarking recommendations by The Orthopaedic Data Evaluation Panel the following parameters will be studied: Clinical parameters such as EQ-5D, Oxford Hip Score and Forgotten Joint Score, preoperative and after 1, 3, 6 and 10 years. Conventional radiography will be done preoperatively, postoperatively, 3, 6 and 10 years after total hip replacement. CTMA will be done postoperatively, 3 and 6 month and 2 years after total hip replacement.

注册库
clinicaltrials.gov
开始日期
2020年8月1日
结束日期
2030年8月1日
最后更新
3年前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

发起方
Sahlgrenska University Hospital, Sweden
责任方
Principal Investigator
主要研究者

Maziar Mohaddes Ardebili

Sahlgrenska University Hospital, Sweden

Sahlgrenska University Hospital, Sweden

入排标准

入选标准

  • Primary hip replacement
  • Eligible for uncemented fixation of the acetabular component
  • Suitable for one of the stem designs from Stryker Orthopaedics
  • Accepts follow-up according to the study protocol

排除标准

  • Difficulties to understand written information due to language problems or other reasons
  • Use of augments needed
  • Acute hip fracture
  • Tumor in the hip joint

结局指标

主要结局

Implant survival at 3 years

时间窗: 3 years

Kaplan Meier survival data, cup revision and risk of revision used as endpoints

次要结局

  • EQ-5D(10 years)
  • Adverse events using the regional VEGA database(10 years)
  • Implant migration measured with Computer Tomography Microanalysis in a subcohort of patients motion Analysis (CTMA) in a sub-cohort of patients(CTMA will be done postoperatively, 3 month and 6 months and 2 years after total hip replacement)
  • Plain radiographs in a sub-cohort of patients(10 years)
  • Implant survival at 10 years(10 years)
  • Adverse events using the national patient register(10 years)
  • Oxford Hip Score(10 years)
  • Forgotten Joint Score(10 years)

研究点 (1)

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