NCT07616466已完成不适用

The Use of Prophylactic Antibiotics in the Endoscopic Secondary Prevention of Cirrhotic Patients With Gastoesophageal Varices: a Retrospective Study

Second Affiliated Hospital, School of Medicine, Zhejiang University1 个研究点分布在 1 个国家目标入组 480 人开始时间: 2024年1月1日最近更新: 2026年6月1日

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 480
试验地点: 1

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

Whether prophylactic antibiotics should be administered in the endoscopic secondary prevention of GVB or not is unclear. In this retrospective study, we are aimed to evaluate whether prophylactic antibiotics confer advantages in the endoscopic secondary prevention of cirrhotic patients with gastroesophageal varices.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 80 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Cirrhotic patients with a history of gastroesophageal variceal bleeding who were readmitted for elective endoscopic treatment.

排除标准

•(1) Age < 18 or ≥ 81 years; (2) Allergy to cephalosporin; (3) Agranulocytosis (neutrophil count < 0.5 × 10^9/L); (4) Massive ascites; and (5) Signs of bacteria infection.
•Withdraw Criteria:（1）Transferred to other department for additional treatment after the endoscopic operation (Surgical department for malignant tumor, Interventional radiology department for splenic embolism or transjugular intrahepatic portosystemic shunt, etc.). （2）Lost to follow-up

研究者

发起方

Second Affiliated Hospital, School of Medicine, Zhejiang University

申办方类型

Other

责任方

Sponsor

研究点 (1)

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