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Clinical Trials/NCT05699369
NCT05699369
Recruiting
Not Applicable

A Cluster Randomised Controlled Trial to Evaluate the Effectiveness of Digital Health Interventions in Improving Non-communicable Disease Management During the Pandemic in Rural Pakistan

University of Toronto1 site in 1 country1,500 target enrollmentJanuary 25, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Noncommunicable Diseases
Sponsor
University of Toronto
Enrollment
1500
Locations
1
Primary Endpoint
Systolic blood pressure (mmHg) measured in the rural health center
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

This randomized controlled trial aims to implement and evaluate a comprehensive package of digital health interventions for integrated COVID-non-communicable diseases (NCDs) care to manage NCDs in primary care facilities in rural Pakistan. The main questions it aims to answer are 1) whether such interventions are effective; 2) how they were implemented; and 3) whether such interventions are cost-effective.

30 rural health centers in Punjab Province, Pakistan will be randomized into two groups. The intervention group will provide a comprehensive package of digital health interventions to connect patients, patient champions, and public health providers to improve the management of NCDs during the pandemic, including 1) providing training to health providers regarding an integrated NCD-COVID guideline; 2) using a smartphone app to improve NCD case management and linking with patient champions; and 3) employing telementoring platform to improve quality of care. Usual care will be provided in the control group. Researchers will compare the two groups to see if the systolic blood pressure can be controlled better in the intervention group at 10 months.

Registry
clinicaltrials.gov
Start Date
January 25, 2023
End Date
February 15, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Xiaolin Wei

Professor

University of Toronto

Eligibility Criteria

Inclusion Criteria

  • Reside in the catchment of selected rural health centers;
  • Provide informed consent;
  • Newly diagnosed of hypertension, i.e., having a baseline blood pressure reading (recorded from the second blood pressure reading using a validated electronic blood pressure machine) of more than 140/90 mmHg; or who is an existing hypertensive patient but with uncontrolled blood pressure with a baseline blood pressure over 140/90 mmHg;
  • Have a smartphone or can access a smartphone from a relative.

Exclusion Criteria

  • Patients having an acute cardiovascular event in the last three months, terminal disease, or other conditions that the rural health center staff determine that will make participation impossible.

Outcomes

Primary Outcomes

Systolic blood pressure (mmHg) measured in the rural health center

Time Frame: At 10 months

Secondary Outcomes

  • Proportion of participants been admitted to district hospitals for any reasons(During the 10-month intervention period)
  • Diastolic blood pressure (mmHg) measured in the rural health center(At 10 months)
  • Systolic and diastolic blood pressure(At 6 months)
  • Percentage of patients with controlled blood pressure measured below 140/90 mmHg for patients with hypertension but without diabetes, and below 130/80 mmHg for patients with diabetes(At 10 months)
  • Body mass index (BMI)(At 10 months)
  • Random blood glucose (mmol/L)(At 10 months)
  • Number of consultations with RHC doctors, including both in-person and virtual consultations(During the 10-month intervention period)
  • Proportion of patients who have had at least three doses of COVID vaccinations(At 10 months)
  • All-cause mortality rate(During the 10-month intervention period)

Study Sites (1)

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