ISRCTN58810841已完成不适用
Endocrine-metabolic and body composition effects of metformin administration in prepubertal children with a low birthweight for gestational age, postnatal catch-up growth, and risk markers for metabolic syndrome: a double-blind randomised placebo-controlled trial
Hospital Sant Joan de Deu (Spain)0 个研究点目标入组 52 人开始时间: 2009年2月27日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Prepubertal children, both males and females
- •2. Birthweight less or equal to -2.0 SDS for gestational age, at term (37-42 week)
- •3. Postnatal catchup (weight and height >p25 in the first 2 years of life)
- •4. Body Mass Index (BMI) >p75 and 5. Increased visceral fat (MR): >p75
- •6. Insulin-like growth factor-I (IGF-I) levels >p75
- •7. Fasting insulin >p75
排除标准
- •1. Syndromatic, chromosomal, or infectious origin of Small for Gestational Age (SGA)
- •2. Gestational diabetes
- •3. Hypothyroidism
- •4. Systemic disease
- •5. Precocious pubarche
- •6. Precocious puberty
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