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Clinical Trials/NCT07543549
NCT07543549
Not yet recruiting
Not Applicable

Variable Manifestations and Outcomes of Renal Diseases Among Children Presenting to the Emergency Room at Sohag University Hospitals

Sohag University0 sites50 target enrollmentStarted: June 5, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
50
Primary Endpoint
Frequency of Clinical Presentations and Final Diagnoses of Pediatric Renal Diseases

Overview

Brief Summary

Renal diseases in children present with a wide spectrum of clinical manifestations, ranging from mild urinary abnormalities to severe acute kidney injury requiring urgent management. Early recognition in the emergency setting is essential to improve outcomes, yet data on pediatric renal emergencies in Upper Egypt remain limited.

This prospective cohort study aims to characterize the clinical presentations of renal diseases among children presenting to the emergency room at Sohag University Hospitals, determine the prevalence of specific renal conditions, and evaluate immediate management outcomes and short-term follow-up after discharge.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
1 Month to 18 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Children aged 1 month to 18 years. Presentation to the emergency room at Sohag University Hospitals with signs and/or symptoms suggestive of renal involvement (e.g., edema, hematuria, oliguria/anuria, flank pain, hypertension).
  • Patients with a known history of renal disease presenting with acute exacerbation.
  • Written informed consent obtained from parents or legal guardians.

Exclusion Criteria

  • Incomplete or missing essential clinical, laboratory, or imaging data. Refusal or inability to obtain written informed consent from parents or legal guardians.
  • Patients with suspected renal symptoms later confirmed to have non-renal causes.
  • Patients who received renal replacement therapy prior to presentation at another facility.

Arms & Interventions

Pediatric patients with renal diseases

Intervention: Standard emergency room management (Other)

Outcomes

Primary Outcomes

Frequency of Clinical Presentations and Final Diagnoses of Pediatric Renal Diseases

Time Frame: At baseline (emergency room presentation) through hospital stay (up to discharge, typically within 7 days)

Percentage (%) of patients presenting with specific clinical features (e.g., edema, hematuria, oliguria, hypertension) assessed by clinical examination and initial laboratory investigations. Distribution (%) of final diagnoses (e.g., acute kidney injury, urinary tract infection, congenital anomalies, glomerular diseases) based on clinical evaluation, laboratory results, and imaging studies.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Fady Medhat Farouk

Pediatric resident

Sohag University

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