Testing for sepsis in primary care: diagnostic and prognostic study investigating the potential benefits of point-of-care testing

Completed

• Conditions: life-threatening infection; Sepsis; 10019815

• Registration Number: NL-OMON48847
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-04-07
• Results First Posted: 2021-09-01
• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 357

Inclusion Criteria

1)Adult patients (*18 years)
2)Home visit by a general practitioner from an out-of-hours service
3)Acutely ill patients with fever, confusion or general deterioration or
otherwise suspected of a serious infection.

Exclusion Criteria

1) No informed consent
2) Non-infectious cause of the acute complaints, e.g. stroke or myocardial
infarction.
3) Hospitalisation less than 7 days before the home visit.
4) Condition that requires secondary care assessment in case of any signs of
systemic infection (eg chemotherapy with possible neutropenia).
5)Terminal illness or other reason not to refer the patient to a hospital
despite presence of a life-threatening condition.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome is diagnosis of sepsis within 72 hours of inclusion.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes are severity of sepsis, 30-day mortality, hospital and ICU<br /><br>admission within 72 hours and length of hospital stay. </p><br>