Sarcopenia and Osteoporosis in the Patients With Hemophilia
- Conditions
- HemophiliaHemophilic ArthropathySarcopeniaOsteoporosis, Osteopenia
- Registration Number
- NCT04535180
- Lead Sponsor
- Tri-Service General Hospital
- Brief Summary
Hemophilia is a bleeding disorder and repeated joint bleeding leads to hemophilic arthropathy. Among patients with hemophilia, vitamin D deficiency and hemophilic arthropathy have been associated with osteoporosis in several clinical studies.There is no data on the prevalence of osteoporosis in hemophilia patients in Taiwan or Asia. To the best of our knowledge, no previous studies have reported the prevalence of sarcopenia and correlation with osteoporosis in hemophilia adult patients. This study will investigate the prevalence and corelation of sarcopenia and low BMD in patients with hemophilia.
patients in Taiwan. The study will estimate the prevalence of sarcopenia and body composition in the hemophilia population and compared baseline demographic and clinical characteristics between the non-sarcopenia and sarcopenia individuals, with particular emphasis on the overlap with osteoporosis and hemophilic arthropathy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
- Hemophilia patients
- History of total hip arthroplasty
- History of instrumentation in lumbar spine
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sacropenia up to 4 weeks Extremity skeletal muscle mass will be calculated using the values measured via the DXA
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
Tri-Service General Hospital
🇨🇳Taipei, Taiwan
Tri-Service General Hospital🇨🇳Taipei, Taiwan