Initial Systolic Time Interval as a predictor of intradialytic hypotensio

Completed

• Conditions: haemodialysis; kidney failure; 10029149

• Registration Number: NL-OMON36975
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

All patients who are treated with chronic intermittent haemodialysis at the dialysis unit of the VU University medical center.

Exclusion Criteria

Younger than 18 years of age; medical, ethical and practical drawbacks or objections to participate. Patients with a pacemaker or implantable cardioverter-defibrillator (ICD) will be excluded.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The study parameters are ISTI, delta-ISTI (respiratory variation in ISTI),<br /><br>RR-interval, delta-RR (respiratory variation in RR-interval), ISTI/RR,<br /><br>delta-ISTI/RR (respiratory variation in ISTI) systolic, diastolic and mean<br /><br>bloodpressure, haematocrit value and calf impedance. Also the occurrence of<br /><br>hypotensive periods will be recorded.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Relative blood volume (RBV), total bodywater, extracellular water and calf<br /><br>extracellular resistance in order to compare parameters derived from ISTI with<br /><br>more traditional markers of haemodynamic status during haemodialyis . These<br /><br>markers will be combined in order to establish the most predictive model for<br /><br>the occurrence of intradialytic hypotension. Also descriptive and<br /><br>anthropometric data will be collected.</p><br>