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A clinical study to assess the effects of two drugs, atorvastatin and pioglitazone in patients of high blood pressure or angina, but without diabetes

Not Applicable
Completed
Registration Number
CTRI/2008/091/000169
Lead Sponsor
I
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients with stable angina between 35-65 years belonging to both sexes.
Patients with hypertension between 35-65 years belonging to both sexes

Exclusion Criteria

Diabetes mellitus
Hepatic/renal dysfunction
Tobacco consumption in any form within previous 6 months
Pregnant or lactating women
CHF [NYHA class II TO IV]
Recent myocardial infarction
History of unstable angina.
History of allergy to statins or pioglitazone
Severe or uncontrolled hypertension(>160/110 mmHg)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical and Biochemical markers of endothelial dysfunctionTimepoint: 0 and 12 weeks(Before and after intervention)
Secondary Outcome Measures
NameTimeMethod
Comparison of side effects between the 3 study armsTimepoint: 2 weekly telephonic history during the 12 week treatment period.
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