An Exploratory Study of the Use of Oral Fluency as a Predictive Tool for the Antidepressant Response of Elderly With Unipolar Depressive Disorder
试验速览
- 阶段
- 不适用
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Ability of the verbal fluency test score to predict the response to antidepressive treatment
研究概览
简要总结
The study focuses on the identification of clinical, physiological and morphological markers that could predict the response to antidepressant in elderly suffering from unipolar depressive disorder.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Depressive episode according to DSM-5 criteria
- •Unipolar depression
- •MADRS ≥ 20
- •Antidepressive treatment (Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors)
排除标准
- •Other comorbid mental disorders (bipolar disorder, schizophrenia, recent addiction < 3 months except for tobacco)
- •Depression with psychotic features
- •Serious unstabilized somatic illness
- •Protected persons
- •Dementia suspected at the time of enrollment
研究组 & 干预措施
Single arm
Psychiatric interview, Neuropsychological evaluations, cardiovascular risk assessment
干预措施: Neuropsychological evaluations (Other)
Single arm
Psychiatric interview, Neuropsychological evaluations, cardiovascular risk assessment
干预措施: Psychiatric interview (Other)
Single arm
Psychiatric interview, Neuropsychological evaluations, cardiovascular risk assessment
干预措施: Cardiovascular risk assessment (Other)
结局指标
主要结局
Ability of the verbal fluency test score to predict the response to antidepressive treatment
时间窗: week 10
verbal fluency is assessed during the neuropsychological assessment
次要结局
未报告次要终点