Correlation Between Quality of Life and Severity of Parkinson's Disease
- Conditions
- Parkinson DiseaseQuality of Life
- Registration Number
- NCT04110106
- Lead Sponsor
- R.O.M.A. - Rehabilitation & Outcome Measures Assessment
- Brief Summary
This study aim to evaluate the correlation between Quality of Life (QoL) and severity of Parkinson's Disease (PD) by assessing the presence of an optimal cut-off point on the Parkinson's disease questionnaire (PDQ-39) as related to the Hoehn \& Yahr (H\&Y) scale in a cohort of Italian adults with PD.
A multicenter, cross-sectional study was performed in central and northern Italy. This study was conducted on a cohort of consecutive individuals at three neurologic outpatient clinics. All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H\&Y scale by a neurologist. Receiver operating characteristic (ROC) curves and coordinates of the curve, which were visually inspected, were used to find cut-off points with optimal sensitivity and specificity. These were in turn used to determine the optimal PDQ-39 cut-off score for identifying disease severity according to H\&Y stages.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 513
- age > 50 but < 90 years,
- H&Y stages I, II, III, and IV,
- a mini-mental state examination > 22 points,
- a minimum level of five years of education.
- Individuals with emotional or psychiatric problems (as determined by clinical screening)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Parkinson's Disease questionnaire (PDQ-39) at admission to the neurologic outpatient clinics quality of life
Hoehn & Yahr (H&Y) at admission to the neurologic outpatient clinics severity of Parkinson's disease
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Human Neurosciences, Sapienza University of Rome
🇮🇹Roma, RM, Italy