ISRCTN50922450CompletedNot Applicable
Biochemical effects of lipopolysaccharide (LPS) adsorber treatment during cardiac surgery using cardio-pulmonary bypass
Papworth Hospital NHS Foundation Trust (UK)0 sites16 target enrollmentStarted: April 22, 2008Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 16
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Age >18 years, both male and female
- •2. Patients scheduled for elective complex combined cardiac surgery using CPB
- •3. Patients scheduled to have cardiac surgery with estimated CPB time in excess of 60 minutes
- •4. Informed consent
Exclusion Criteria
- •1. Planned hypothermia (core temperature <28°C) during surgery
- •2. Use of steroids in last six months
- •3. Undergoing immunosuppressive therapy
- •4. Anaemia (preoperative haemoglobin <10 g/dL)
- •5. Haematological malignancy
- •6. Disease of the immune system
- •7. Female patients of childbearing age
- •8. Participation in another clinical trial
Investigators
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