Cytokine expression patterns in patients with traumatic Spinal Cord Injury
Recruiting
- Conditions
- T09.3G95.9Injury of spinal cord, level unspecifiedDisease of spinal cord, unspecified
- Registration Number
- DRKS00009917
- Lead Sponsor
- Oberarzt der Unfall- und Wiederherstellungschirurgie Universitätsklinik Heidelberg Department für Orthopädie, Unfallchirurgie und Paraplegiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
Patient with acute traumatic Spinal Cord Injury
Exclusion Criteria
non-traumatic spinal cord injury, traumatic brain injury (TBI), severe abdominal trauma, traumatic amputation of extremities and coma. Participants were given neither methylprednisolone sodium succinate (MPSS) nor nonsteroidal anti-inflammatory drugs (NSAIDs) during study participation.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ASIA score* after 3 months<br><br>*This is a system of tests used to define and describe the extent and severity of a patient’s spinal cord injury and help determine future rehabilitation and recovery needs. The patient’s grade is based on how much sensation he or she can feel at multiple points on the body, as well as tests of motor function.<br><br>ASIA (ASIA Impairment Scale)<br>Grade A<br>Complete lack of motor and sensory function below the level of injury (including the anal area)<br>Grade B<br>Some sensation below the level of the injury (including anal sensation)<br>Grade C<br>Some muscle movement is spared below the level of injury, but 50 percent of the muscles below the level of injury cannot move against gravity.<br>Grade D<br>Most (more than 50 percent) of the muscles that are spared below the level of injury are strong enough to move against gravity.<br>Grade E<br>All neurologic function has returned.
- Secondary Outcome Measures
Name Time Method eurological Remission according to ASIA Score after 3 months (Examinating wheather the patient had a neurological improvement or not)