Pilot Study of Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Change in feasibility of using a single question to assess prognostic understanding in patients, caregivers, and clinicians
研究概览
简要总结
This trial assesses the quality of life in patients with high grade glioma and their caregivers using a questionnaire called the Beacon Patient Related Outcomes Quality of Life (PROQOL). Knowledge gained from this trial may help researchers find out if early integration of palliative care will lead to improvement in quality of life for both patients and caregivers.
详细描述
PRIMARY OBJECTIVES:
I. Assess feasibility of intra-office Beacon Patient Related Outcomes Quality of Life Scale (PROQOL) assessment of patient and caregiver.
II. Assess feasibility of routine (monthly) visits with palliative care specialists.
III. Evaluate if overall quality of life of patients with high grade glioma and their caregivers improves with identifying and addressing symptoms and psychosocial concerns identified through the PROQOL tool.
IV. Evaluate if overall quality of life of patients with high grade glioma improves further with early integration of palliative care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults with pathology confirmed high grade glioma, graded as World Health Organization (WHO) grade III and IV
- •Ability to use a tablet
- •Able to adhere to completing surveys at study visits
- •English speaking
- •Has a caregiver that has provided oral consent to participate in this study
- •Insurance accepted at Mayo Clinic Arizona
排除标准
- •Inability to use a tablet
- •Inability to adhere to completing surveys at monthly visits
- •Unable to speak English
- •Lack of a caregiver
- •Insurance not accepted at Mayo Clinic Arizona
研究组 & 干预措施
Group A (visit with neuro-oncologist)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months to address concerns that are identified via the survey and the domain of concern identified by patient and caregiver.
干预措施: Quality-of-Life Assessment (Other)
Group A (visit with neuro-oncologist)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months to address concerns that are identified via the survey and the domain of concern identified by patient and caregiver.
干预措施: Supportive Care (Other)
Group A (visit with neuro-oncologist)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months to address concerns that are identified via the survey and the domain of concern identified by patient and caregiver.
干预措施: Survey Administration (Other)
Group B (visit with neuro-oncologist and palliative care team)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist and palliative care team monthly for 6 months to address concerns that are identified by the survey and domains of concerns. Caregivers also attend support sessions led by a social worker monthly for 6 months.
干预措施: Palliative Therapy (Other)
Group B (visit with neuro-oncologist and palliative care team)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist and palliative care team monthly for 6 months to address concerns that are identified by the survey and domains of concerns. Caregivers also attend support sessions led by a social worker monthly for 6 months.
干预措施: Quality-of-Life Assessment (Other)
Group B (visit with neuro-oncologist and palliative care team)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist and palliative care team monthly for 6 months to address concerns that are identified by the survey and domains of concerns. Caregivers also attend support sessions led by a social worker monthly for 6 months.
干预措施: Supportive Care (Other)
Group B (visit with neuro-oncologist and palliative care team)
Patients and primary caregiver complete the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist and palliative care team monthly for 6 months to address concerns that are identified by the survey and domains of concerns. Caregivers also attend support sessions led by a social worker monthly for 6 months.
干预措施: Survey Administration (Other)
Group C (visit with neuro-oncologist, palliative care team)
Patients and primary caregiver complete quality of life portion of the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months and address important concerns that come up on the survey. Patients may also receive palliative care consultation as deemed appropriate by the neuro-oncologist.
干预措施: Palliative Therapy (Other)
Group C (visit with neuro-oncologist, palliative care team)
Patients and primary caregiver complete quality of life portion of the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months and address important concerns that come up on the survey. Patients may also receive palliative care consultation as deemed appropriate by the neuro-oncologist.
干预措施: Quality-of-Life Assessment (Other)
Group C (visit with neuro-oncologist, palliative care team)
Patients and primary caregiver complete quality of life portion of the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months and address important concerns that come up on the survey. Patients may also receive palliative care consultation as deemed appropriate by the neuro-oncologist.
干预措施: Supportive Care (Other)
Group C (visit with neuro-oncologist, palliative care team)
Patients and primary caregiver complete quality of life portion of the BEACON PROQOL survey before each visit. Patients then receive standard of care for high grade glioma consisting of visits with neuro-oncologist monthly for 6 months and address important concerns that come up on the survey. Patients may also receive palliative care consultation as deemed appropriate by the neuro-oncologist.
干预措施: Survey Administration (Other)
结局指标
主要结局
Change in feasibility of using a single question to assess prognostic understanding in patients, caregivers, and clinicians
时间窗: monthly for 6 months
At each visit, patients, their caregivers, and the clinicians will be asked to estimate survival time left with options being weeks, weeks to months, several months to years, indefinite number of years, or they may choose not to answer.
Change in feasibility of using the Beacon Patient Reported Outcomes Quality of Life Scale (PROQOL)
时间窗: monthly for six months
Patients will be randomized to 3 groups - Control (standard of care); Arm A (PROQOL + standard of care); Arm B (early palliative care + Arm A). Feasibility of conducting the assessment at monthly visits for each patient/caregiver cluster, along with early involvement of palliative care, will be assessed.
次要结局
- Discordance in prognostic understanding over time(Up to 6 months.)
- Quality of life of patients and caregivers(Up to 6 months)
研究者
Alyx Porter, M.D.
Principal Investigator
Mayo Clinic