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Clinical Trials/NCT03249922
NCT03249922
Terminated
Not Applicable

A Prospective Analysis of Quality of Life Outcomes in Spinal Cord Stimulation

Rutgers, The State University of New Jersey1 site in 1 country6 target enrollmentOctober 27, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neuropathic Pain
Sponsor
Rutgers, The State University of New Jersey
Enrollment
6
Locations
1
Primary Endpoint
The number of patients with at least 50% improvement in VAS Pain Score
Status
Terminated
Last Updated
7 years ago

Overview

Brief Summary

The investigators will be evaluating quality of life outcomes in patients who are undergoing routine spinal cord stimulator implant for uncontrolled pain. Patients will be evaluated pre and post-operatively for quality of life improvements, pain control, and functionality.

Detailed Description

This is a prospective cohort study for patients who will be undergoing implantation of spinal cord stimulator for pain. All patient will have implantation done at University Hospital Newark or Newark Beth Israel. The data points that will be collected will be the patient's weight, BMI, and detailed questionnaires regarding disability, activity, quality of life, and depression. The first data set will be taken pre-operatively at the DOC, 90 Bergen Street, suite 8100. Those patients enrolled will have the same data taken again upon subsequent postoperative visits at 3, 6, and 12 months. Being that spinal cord stimulation is a well-documented safe procedure, the investigators do not anticipate any deviation from the standard risks of surgery. With that being said the primary safety endpoint would be if there is an increased complication rate, secondary to the procedure, greater than the current anticipated risk rate. This is a purely observational study. Patients are not being recruited for an intervention but are being recruited during routine clinical practice.

Registry
clinicaltrials.gov
Start Date
October 27, 2017
End Date
July 22, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Antonios Mammis MD

Director, Center for Neuromodulation

Rutgers, The State University of New Jersey

Eligibility Criteria

Inclusion Criteria

  • Patients with neuropathic pain or axial back pain that is not controlled by oral analgesics, opioids, and has failed conservative management.
  • Ages 18-90 with no ethnicity or gender predilections.

Exclusion Criteria

  • Patients who have spinal cord injury, multiple stimulator revisions, DRG stimulators, intrathecal pain pumps, complex regional pain syndrome, previous spinal cord stimulator implant, mechanical instability requiring fusion, myelopathy, psychological condition precluding them from complying with therapy, illegal drug abuse including heroin, cocaine, and illegally obtained prescription pills, or have previously been or are currently involved in litigation for medical malpractice.

Outcomes

Primary Outcomes

The number of patients with at least 50% improvement in VAS Pain Score

Time Frame: 12 Months

The number of patients who had at least 50% improvement in VAS pain score

The number of patients with at least 50% improvement in Owenstry low back disability index

Time Frame: 12 Months

The number of patients who had at least 50% improvement in disability as determined by this questionnaire.

The number of patients with at least 50% improvement in WHODAS 12 disability index.

Time Frame: 12 Months

The number of patients who had at least 50% improvement in disability as determined by this questionnaire.

Secondary Outcomes

  • The number of patients with at least 50% improvement in SF-36 quality of life score(12 months)
  • The number of patients with at least 50% improvement in beck depression inventory(12 Months)

Study Sites (1)

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