Evaluation of different methods to measure muscle mass and strength in a population with class II/III obesity: A Cross-Sectional Study

Completed

• Conditions: morbide obesitas; Obesity Overweight

• Registration Number: NL-OMON54850
• Lead Sponsor: Medisch Centrum Leeuwarden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-06-24
• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 84

Inclusion Criteria

- Between 18 and 65 years of age.
- BMI above 35 kg/m2

Exclusion Criteria

- History of bariatric surgery
- Inability to perform physical tests
- Inability to communicate in either Dutch or English
- Weight over 204 kilograms (due to limitations of the DEXA)
- BMI above 50 kg/m2
- Pregnancy
- Pacemaker

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main parameters: muscle mass measured by DEXA, ultrasound (US), bioelectrical<br /><br>impedance analysis (BIA), anthropometric methods and 24-hour urine creatinine.<br /><br>Main endpoint: correlation between muscle mass measured by DEXA and one of the<br /><br>parameters.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary parameters: muscle strength measured by handgrip strength;<br /><br>biochemical measures; protein intake; and physical activity measured with<br /><br>movement sensors and short questionnaire to assess health-enhancing physical<br /><br>activity (SQUASH).<br /><br>Secondary endpoint: the correlation between multiple parameters for muscle mass<br /><br>and muscle strength and the muscle mass measured by DEXA.</p><br>