Acupuncture for Symptoms of Nerve Damage

Not Applicable

Completed

• Conditions: Chemotherapy-induced Peripheral Neuropathy; Peripheral Neuropathy
• Interventions: Procedure: Acupuncture; Procedure: Sham Acupuncture; Other: Usual Care Group; Behavioral: questionnaires

• Registration Number: NCT03183037
• Lead Sponsor: Memorial Sloan Kettering Cancer Center

Brief Summary

The purpose of this study is to compare the effects of real acupuncture with placebo acupuncture or usual care on symptoms of nerve damage from chemotherapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-07
• Study First Submitted: 2017-06-08
• Study First Submitted QC: 2017-06-08
• Study First Posted: 2017-06-09
• Status Verified: 2024-05
• Primary Completion: 2024-05-02
• Study Completion: 2024-05-02
• Last Update Submitted: 2024-05-02
• Last Update Posted: 2024-05-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• English-speaking
• Age ≥ 18 years old
• Solid tumor survivors with no evidence of disease
• Moderate to severe CIPN, defined by symptoms such as numbness, tingling, or pain ratings of 4 or greater on a 0-10 numeric rating scale (NRS)
• Have completed neurotoxic chemotherapy at least 3 months prior to enrollment
• If taking anti-neuropathy medications, they are on a stable regimen (no change in 3 months)

Read More

Exclusion Criteria

• Patients with a pacemaker
• Prior acupuncture treatment within 5 years of enrollment

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Acupuncture Treatment Group	Acupuncture	Ten acupuncture treatments over the course of eight weeks, with twice weekly acupuncture treatments for the first two weeks, and then weekly treatment thereafter.
Acupuncture Treatment Group	questionnaires	Ten acupuncture treatments over the course of eight weeks, with twice weekly acupuncture treatments for the first two weeks, and then weekly treatment thereafter.
Sham Acupuncture Treatment Group	Sham Acupuncture	Ten sham acupuncture treatments over the course of eight weeks, with twice weekly sham acupuncture treatments for the first two weeks, and then weekly sham acupuncture treatment thereafter.
Sham Acupuncture Treatment Group	questionnaires	Ten sham acupuncture treatments over the course of eight weeks, with twice weekly sham acupuncture treatments for the first two weeks, and then weekly sham acupuncture treatment thereafter.
Usual Care Group	Usual Care Group	Twelve weeks of usual care.
Usual Care Group	questionnaires	Twelve weeks of usual care.

Primary Outcome Measures

Name	Time	Method
change in the proportion of patients with a CIPN severity	up to 12 weeks	according to the NCI-CTC 4.0

Trial Locations

Locations (2)

Memorial Sloan Kettering Cancer Center @ Commack; 🇺🇸 Commack, New York, United States

Memorial Sloan Kettering Cancer Center; 🇺🇸 New York, New York, United States