Comparing Electrical Impedance Tomography to Computed Tomographic Angiography

Active, not recruiting

• Conditions: Pulmonary Embolism
• Interventions: Device: Electrical impedance tomography

• Registration Number: NCT05546333
• Lead Sponsor: Colorado State University

Brief Summary

The study aim is to determine whether electrical impedance tomography (EIT) is equivalent in the detection of pulmomary emboli compared to Computed Tomographic Angiography (CTA). EIT is a non-invasive, non-ionizing functional imaging technique that can be performed at bedside. Electrical impedance tomography data will be collected on individuals undergoing a CTA scan of the chest at Medical Center of the Rockies (MCR). The primary outcome measure is to assess whether assessment by CTA corresponds with EIT in detection of pulmonary emboli. The study will include up to 63 participants. EIT data will be collected for up to 20 minutes during tidal breathing and for approximately five to ten seconds during breath-holding.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-09-15
• Study First Submitted QC: 2022-09-15
• Study First Posted: 2022-09-19
• Study Start: 2023-05-01
• Status Verified: 2024-05
• Primary Completion: 2024-05-23
• Last Update Submitted: 2024-05-24
• Last Update Posted: 2024-05-28
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

• 18 years of age or older
• Undergoing a CTA of the chest at MCR

Exclusion Criteria

• Under 18 years of age
• Body mass index (BMI) > 30
• Individuals with known thoracic metal implants or devices, such as pacemakers (internal and external), staples, or spinal and rib hardware
• Individuals deemed by the research team as too unstable to safely apply the EIT belt, such as hemodynamic or respiratory instability (e.g., intubated patients), and individuals with unstable spinal injuries
• Open wounds at the site of electrode belt application

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients receiving CTA	Electrical impedance tomography	Patients who will receive a CTA due to clinical need will be imaged with electrical impedance tomography in addition to the CTA.

Primary Outcome Measures

Name	Time	Method
Correspondence to CTA	One year	To assess whether assessment by CTA corresponds with EIT in detection of pulmonary emboli (PE).

Trial Locations

Locations (1)

UCHealth Medical Center of the Rockies; 🇺🇸 Loveland, Colorado, United States