Phase I/II study of nedaplatin, a cisplatin analogue, and S-1 in patients with advanced squamous cell lung carcinoma.
- Conditions
- advanced squamous cell lung carcinoma
- Registration Number
- JPRN-UMIN000003332
- Lead Sponsor
- Keio University School of Medicine, division of Pulmonary Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 45
Not provided
1.History of grave drug allergic reaction 2.Patients under treatment with phenytoin or flucytosine. 3.Serious complications (e.g. intestinal paralysis, intestinal obstruction, interstitial pneumonia or fibroid lung detectable on chest X-ray films , poorly controlled diabetes, heart failure, renal failure, hepatic failure, or haemorrhagic peptic ulcer etc.). Serious medical complications 4. History of poorly controlled pleural effusion,pericardial effusion and ascites . 5.Symptomatic brain metastasis 6.Patients with uncontrolled water diarrhea or chronic constipation. 7.Active double cancer. Carcinoma in situ and lesions of intramucosal carcinoma will not be included in active double cancer and will be permitted for registration. 8.Pregnant females, possibly pregnant females, females wishing to become pregnant and nursing mothers. 9.Males that are currently attempting to produce a pregnancy. 10.Inadequate physical condition, as diagnosed by primary physician.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method