Changes in Brain Activity (Functional MRI Study) Before and After Behavioral Therapy of Height Phobia

Not Applicable

Completed

• Conditions: Height Phobia; Fear of Heights

• Registration Number: NCT00302978
• Lead Sponsor: New York State Psychiatric Institute

Brief Summary

We are interested in investigating the functional brain abnormalities of height phobia. Subjects will be have a functional MRI scan before and after a course of treatment with behavioral therapy.

Detailed Description

The purpose of this study is to investigate the effects of in vivo exposure therapy on the functional brain activity of subjects with height phobia using a fear provocation paradigm. We expect differential activation of the fear circuitry in height phobics compared to non-phobic controls, and that successful behavioral therapy will normalize the heightened fear response in height phobia.

Study Timeline

• Study Start: 2006-03
• Study First Submitted: 2006-03-14
• Study First Submitted QC: 2006-03-14
• Study First Posted: 2006-03-15
• Study Completion: 2006-06
• Status Verified: 2007-04
• Last Update Submitted: 2011-12-14
• Last Update Posted: 2011-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Specific phobia of Heights

Exclusion Criteria

• History of medical problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
CGI

Secondary Outcome Measures

Name	Time	Method
acrophobia questionnaire