Interleukin23 in Systemic Lupus

Not Applicable

Recruiting

• Conditions: Systemic Lupus Erythematosus Related Interstial Lung Disease
• Interventions: Biological: interleukin 23

• Registration Number: NCT06713187
• Lead Sponsor: Sohag University

Brief Summary

assement of interleukin 23 in serum of patients with systemic lupus erythematosus related interstial lung disease .

Detailed Description

for all patients detailed history taken clinical and rhumatological examination will be assessed and SLEDAI score will be collected from the case record of the patients\&laboratory investigation included 1_erythrocytic sedimentation rate.2_complete blood count.3_interleukin23 .4_complement 3\&4.5_Antinuclear Antibodies.6_Anti double stranded antibodies.7_full basic biochemical test(24 urine protien)8_high resolution computed tomography.

Study Timeline

• Status Verified: 2024-11
• Study First Submitted: 2024-11-27
• Study First Submitted QC: 2024-11-27
• Last Update Submitted: 2024-11-27
• Study First Posted: 2024-12-03
• Last Update Posted: 2024-12-03
• Study Start: 2025-05-01
• Primary Completion: 2025-08-01
• Study Completion: 2026-06-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• patients with systemic lupus erythematous and patients with systemic lupus erythematosus with interstial lung disease.

Exclusion Criteria

• patients with chest conditions rather than interstial lung disease &who receiving biological blocking antibodies& those treated with immunosuppressive drugs.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
group2	interleukin 23	Patients with systemic lupus erythematosus with interstial lung disease.
group3	interleukin 23	healthy control groups
group 1	interleukin 23	Patients with systemic lupus erythematosus without interstial lung disease.

Primary Outcome Measures

Name	Time	Method
interleukin 23	2 years	level of interleukin 23 in Sera of patients with systemic lupus erythematosus using ELIZA

Trial Locations

Locations (2)

Sohag university hospital; 🇪🇬 Sohag, Egypt

Sohag university; 🇪🇬 Sohag, Egypt