The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure.
The main questions it aims to answer are:
Does sleep apnea severity improve after fluid removal? Is the improvement in sleep apnea related to the amount of fluid removed? Do changes in neck size reflect changes in sleep apnea severity?
Participants admitted to the hospital with heart failure and fluid overload will take part in this study.
Participants will:
Use a wearable sleep monitoring device (WatchPAT) on the first night of hospitalization Use the device again after fluid removal, when the treating cardiologist determines that the patient is no longer fluid overloaded Have their neck circumference measured before and after fluid removal Have their weight and fluid balance recorded during hospitalization Have routine blood tests and clinical assessments as part of standard care
Researchers will compare each participant's results before and after fluid removal to see if sleep apnea improves and whether these changes are linked to fluid removal and changes in neck circumference.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years or older
- •Hospitalized with decompensated heart failure and clinical evidence of fluid overload
- •Diagnosis of heart failure (reduced or preserved ejection fraction)
- •Clinically indicated for diuretic therapy
- •Able to undergo sleep apnea assessment using the WatchPAT device
- •Able to provide informed consent
排除标准
- •Known central sleep apnea as the predominant sleep-disordered breathing type
- •Current treatment with continuous positive airway pressure (CPAP)
- •Acute respiratory failure requiring mechanical ventilation
- •Conditions preventing proper use of the WatchPAT device (e.g., severe hand or finger injury)
- •Hemodynamic instability precluding participation
- •Pregnancy
研究者
Itshak Amsalem
Principal Investigator
Shaare Zedek Medical Center