D-dimer plasma levels and risk for thromboembolism after surgery for intracranial tumors with intraoperative administration of intermittent pneumatic compression of the legs
Phase 4
- Conditions
- I80.28
- Registration Number
- DRKS00011783
- Lead Sponsor
- Klinik und Poliklinik für Neurochirurgie der Martin-Luther-Universität Halle-Wittenberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 108
Inclusion Criteria
Elective surgery for intracranial pathology via craniotomy.
Exclusion Criteria
Minors or pregnant patients, Administration of blood-products in the perioperative period, abnormal coagulation status, preoperative infection, revision surgery after initial surgery, liver disease, preoperative deep venuous thrombosis or thrombophlebitis. Decompensated cardiac insufficiency, Erysipel, severe arterial hypertonus, soft tissue damage of the lower extremity, neuropathy and occlusion of lymph vessels.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of deep venuous thrombosis in patients undergoing surgery for intracranial pathology with/without IPC, determined by Doppler sonography of the legs within the first week after surgery.
- Secondary Outcome Measures
Name Time Method 1. D-dimer plasma levels on the 3rd postoperative day in patients with/without IPC; threshold for screening?<br>2. Quantification of risk reduction for deep venuous thrombosis by IPC with respect to duration of surgery and other clinical variables