NACER II: Reducing Prenatal Exposures to Household Air Pollution in Rural Guatemala Through a Gas Stove/Behavior Intervention to Improve Neonatal Health
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change in 48-hour mean personal carbon monoxide exposure
研究概览
简要总结
Greater efforts are needed to bring affordable, clean stoves and adaptive behavioral strategies to the millions of households worldwide that continue to burn solid cooking fuels using inefficient stoves. Two of the leading causes of infant mortality, preterm birth and pneumonia, are associated with high exposures to household air pollution during pregnancy and early infancy. The proposed study will assess the feasibility and acceptability of an introduced liquid petroleum gas stove, complemented by two alternative approaches to delivering tailored behavioral change interventions, among pregnant women and their neonates.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant woman less than 20 weeks gestation
- •Does not smoke cigarettes
- •Uses an open fire or deteriorated woodstove for cooking
- •Purchases wood
- •Intends to stay in the study area for at least one year
- •Uses Ministry of Health clinics for routine prenatal care
- •Has a mobile phone
- •Primary person responsible for cooking in the household
- •Able to give Informed Consent
排除标准
- •Multiple pregnancy (eg twins)
- •Identified as a high-risk pregnancy by physician
- •Regularly taking prescription medication
- •Smokes cigarettes
- •Routinely carries a child less than 2 years old on their back
研究组 & 干预措施
Phase 1
In Phase I, 25 pregnant women will receive a low-cost gas stove and will be taught by peer educators in group classes how to safely use gas stoves and how to reduce exposure to air pollution.
干预措施: Low-cost gas stove (Other)
Phase 1
In Phase I, 25 pregnant women will receive a low-cost gas stove and will be taught by peer educators in group classes how to safely use gas stoves and how to reduce exposure to air pollution.
干预措施: Peer education classes (Behavioral)
Phase 2
In Phase 2, the investigators will assess a more resource-intensive behavioral intervention approach with a different group of 25 women who will follow the same study procedures described in Phase I.
干预措施: Low-cost gas stove (Other)
Phase 2
In Phase 2, the investigators will assess a more resource-intensive behavioral intervention approach with a different group of 25 women who will follow the same study procedures described in Phase I.
干预措施: Resource-intensive behavioral intervention approach (Behavioral)
结局指标
主要结局
Change in 48-hour mean personal carbon monoxide exposure
时间窗: 1) <20 weeks gestation; 2) 28-32 weeks gestation; 3) Following participation in each behavior change intervention class at 18-24 weeks, 22-28 weeks, and 26-32 weeks gestation; 4) Neonatal after 48 hours, 2 & 4 weeks of life
Change in urinary polycyclic aromatic hydrocarbon (PAH) and volatile organic compound (VOC) metabolite concentrations
时间窗: 1) <20 weeks gestation; 2) 28-32 weeks gestation
Change in weekly use of gas stoves (cooking events and total cooking time) using temperature loggers
时间窗: Every month from recruitment to neonatal one month of life (up to 9 months)
Change in 48-hour mean kitchen particulate matter concentration
时间窗: 1) <20 weeks gestation; 2) 28-32 weeks gestation; 3) Following participation in each behavior change intervention class at 18-24 weeks, 22-28 weeks, and 26-32 weeks gestation; 4) Neonatal after 48 hours, 2 & 4 weeks of life
Change in 48-hour mean personal particulate matter exposure
时间窗: 1) <20 weeks gestation; 2) 28-32 weeks gestation; 3) Following participation in each behavior change intervention class at 18-24 weeks, 22-28 weeks, and 26-32 weeks gestation; 4) Neonatal after 48 hours, 2 & 4 weeks of life
次要结局
- Preterm birth(At time of birth (within 48 hours))
- Low birth weight(At time of birth (within 48 hours))
- Respiratory illness(up to one month following birth)