PWV for Cardiovascular Complication After Cardiac Surgery

Completed

• Conditions: C.Surgical Procedure; Cardiac

• Registration Number: NCT02014012
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Arterial stiffness has been suggested as an independent risk factor for the development of coronary artery disease and stroke. Pulse wave velocity (PWV) is an noninvasive established index to quantify arterial stiffness. Therefore, we try to investigate the correlation between PWV values and cardiovascular complications like stroke, acute renal failure, or perioperative myocardial infarction after cardiac surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04
• Study First Submitted: 2013-07-31
• Study First Submitted QC: 2013-12-11
• Study First Posted: 2013-12-17
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-10
• Last Update Posted: 2015-04-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Cardiac surgery patients who sign the informed consent

Exclusion Criteria

• Chronic renal failure (Cr>1.5mg/dL), Dialysis patients
• Previous stroke
• Left ventricular dysfunction (EF <50%)
• ASO with claudication
• < 40 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative cardiovascular complication and parameters	within the first 7 days after surgery	Stroke, Delirium, Newly developed atrial fibrillation, ARF, Peak CK-MB and troponin I levels measured at 12 and 24 hours after surgery, Peak estimated GFR and corresponding creatinine

Secondary Outcome Measures

Name	Time	Method
E/e' and e' measured by transthoracic echocardiography with color-coded tissue dopper imaging in patients undergoing non-valvular cardiac surgery	baseline and within the first 14 days after surgery	peak early transmitral filling velocity during early diastole (E), mean early velocity at the septal mitral annulus (e')

Trial Locations

Locations (1)

SMG-SNU Boramae Medical Center; 🇰🇷 Seoul, Korea, Republic of