Evaluation of Pulse Wave Velocity as a Predictive Factor for Postoperative Cardiovascular Complication After Cardiac Surgery: a Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Postoperative cardiovascular complication and parameters
研究概览
简要总结
Arterial stiffness has been suggested as an independent risk factor for the development of coronary artery disease and stroke. Pulse wave velocity (PWV) is an noninvasive established index to quantify arterial stiffness. Therefore, we try to investigate the correlation between PWV values and cardiovascular complications like stroke, acute renal failure, or perioperative myocardial infarction after cardiac surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cardiac surgery patients who sign the informed consent
排除标准
- •Chronic renal failure (Cr>1.5mg/dL), Dialysis patients
- •Previous stroke
- •Left ventricular dysfunction (EF <50%)
- •ASO with claudication
- •< 40 years
结局指标
主要结局
Postoperative cardiovascular complication and parameters
时间窗: within the first 7 days after surgery
Stroke, Delirium, Newly developed atrial fibrillation, ARF, Peak CK-MB and troponin I levels measured at 12 and 24 hours after surgery, Peak estimated GFR and corresponding creatinine
次要结局
- E/e' and e' measured by transthoracic echocardiography with color-coded tissue dopper imaging in patients undergoing non-valvular cardiac surgery(baseline and within the first 14 days after surgery)
研究者
Jae-Sung Choi, MD. PhD.
Associate Professor
Seoul National University Hospital