PWV for Cardiovascular Complication After Cardiac Surgery
- Conditions
- C.Surgical Procedure; Cardiac
- Registration Number
- NCT02014012
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Arterial stiffness has been suggested as an independent risk factor for the development of coronary artery disease and stroke. Pulse wave velocity (PWV) is an noninvasive established index to quantify arterial stiffness. Therefore, we try to investigate the correlation between PWV values and cardiovascular complications like stroke, acute renal failure, or perioperative myocardial infarction after cardiac surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Cardiac surgery patients who sign the informed consent
- Chronic renal failure (Cr>1.5mg/dL), Dialysis patients
- Previous stroke
- Left ventricular dysfunction (EF <50%)
- ASO with claudication
- < 40 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative cardiovascular complication and parameters within the first 7 days after surgery Stroke, Delirium, Newly developed atrial fibrillation, ARF, Peak CK-MB and troponin I levels measured at 12 and 24 hours after surgery, Peak estimated GFR and corresponding creatinine
- Secondary Outcome Measures
Name Time Method E/e' and e' measured by transthoracic echocardiography with color-coded tissue dopper imaging in patients undergoing non-valvular cardiac surgery baseline and within the first 14 days after surgery peak early transmitral filling velocity during early diastole (E), mean early velocity at the septal mitral annulus (e')
Trial Locations
- Locations (1)
SMG-SNU Boramae Medical Center
🇰🇷Seoul, Korea, Republic of