Complications Associated With Central Venous Access in the NSICU: PICC vs CVC

Not Applicable

Completed

• Conditions: PICC; Neuroscience ICU; Central Venous Catheter; Central Line; Neuro ICU; CVC
• Interventions: Device: centrally inserted central catheter; Device: peripherally inserted central catheter

• Registration Number: NCT02314520
• Lead Sponsor: Milton S. Hershey Medical Center

Brief Summary

The goal of this study is to determine whether Peripherally Inserted Central Catheter or Centrally Inserted Venous Catheters have lower complication rates in the Neuroscience Intensive Care Unit. After admission to the Neuroscience ICU and if they require central access, patients will be randomized to receive a PICC or CVC and complications (such as pneumothorax, deep venous thrombosis, infection, etc.) will be tracked and compared between the two interventions.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-11-26
• Study First Submitted QC: 2014-12-10
• Study First Posted: 2014-12-11
• Study Start: 2015-07-13
• Primary Completion: 2016-12-07
• Study Completion: 2016-12-07
• Results First Submitted: 2017-05-23
• Status Verified: 2017-06
• Results First Submitted QC: 2017-06-21
• Last Update Submitted: 2017-06-21
• Results First Posted: 2017-07-19
• Last Update Posted: 2017-07-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 152

Inclusion Criteria

Adult patients admitted to the NSICU, who require central access for the treatment of their illness.

Exclusion Criteria

1. Current or recent (within 1 month) diagnosis of bacteremia
2. Current or recent (within 1 year with confirmed resolution by imaging) deep venous thrombosis
3. Existing central access
4. Non-English speaking
5. Requirement for emergent central access and unable to obtain consent in an emergency setting

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CVC	centrally inserted central catheter	Patients randomly assigned to receive a centrally inserted central catheter and they will be monitored for either having a complication or no complication.
PICC	peripherally inserted central catheter	Patients randomly assigned to receive a peripherally inserted central catheter and they will be monitored for either having a complication or no complication.

Primary Outcome Measures

Name	Time	Method
Participants With Complications With Central Access Including Insertion	up to 10 weeks	Aggregation of all complications associated with central access including insertion

Secondary Outcome Measures

Name	Time	Method
Number of Participants With Deep Venous Thrombosis	up to 10 weeks
Number of Patients With Complications Related to Insertion	From the time of insertion until first confirmatory chest X-ray	Any complication of insertion including technical failure
Number of Participants With a Central Line Associated Blood Stream Infection	up to 10 weeks	A Central access associated infection (CLABSI)

Trial Locations

Locations (1)

Penn State Hershey Medical Center; 🇺🇸 Hershey, Pennsylvania, United States