MedPath

Impact of Daily, Digital and Behavioral Tele-health Tapering Program for Perioperative Surgical Patients Exposed to Opioids and Benzodiazepines.

Not Applicable
Completed
Conditions
Elective Spine Surgery Receiving Pre and/or Postoperative Pain Control With Opioids
Interventions
Behavioral: Opioid and Benzodiazepine Naive-patients
Behavioral: Opioid and Benzodiazepine Tolerant-patients
Registration Number
NCT04787692
Lead Sponsor
The University of Texas Health Science Center, Houston
Brief Summary

The purpose of this study is to examine the safety, acceptability, and feasibility of a controlled taper off of opioids and/or benzodiazepines, with the use of behavioral health tele-health based therapy services, in the perioperative patient.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Preoperative benzodiazepines opioid dependence (daily use of opioids or benzodiazepines preoperatively) (Naive: No Meds 30 Days Prior to surgery,Opioid tolerant/dependant: Use of Meds on Most Days For 1 or more months prior to surgery)
  • Subject willing to use Lucid Lane program to provide behavioral health support perioperative period up to 6 months post-op for tolerant opioid/benzo users
  • Subject is willing to discuss Lucid Lane progress with the University of Texas Health Science Center(UTHealth) perioperative team and prescribing clinicians
  • Subject is willing to sign a Lucid Lane Client Agreement
  • Willing to sign an informed consent
Exclusion Criteria
  • Serious mental illnesses including schizophrenia-spectrum disorders, severe bipolar disorder, and severe major depression.
  • Active suicidal ideations
  • Patients on methadone or buprenorphine for treatment of opioid use disorder (i.e. for treatment of addiction, and not for treatment of pain)
  • Patient unwilling to use or not possessing access to a device that allows for video visits (e.g. a smartphone, tablet, or computer)
  • Patients who are on palliative care
  • Insufficient ability to use English to participate in the consent process, the intervention or study assessments.
  • Insufficient ability to provide informed consent to participate
  • If the patient misses more than 2 lucid lane sessions per week, the staff will be immediately notified by Lucid Lane.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Opioid and Benzodiazepine Naive-patientsOpioid and Benzodiazepine Naive-patientsOpioid and Benzodiazepine Naive-patients, defined as no medications 30 days prior to surgery
Opioid and Benzodiazepine Tolerant-patientsOpioid and Benzodiazepine Tolerant-patientsOpioid and Benzodiazepine Tolerant-patients, defined as use of medications on most days for 1 or more months (\>30 days) prior to surgery
Primary Outcome Measures
NameTimeMethod
Number of patients that engage and participate in the process180 days post intervention

Engagement and participation are defined as patient's commitment for 1 hour a week as scheduled.

Secondary Outcome Measures
NameTimeMethod
Emotional well-being as measured by the The Patient Health Questionnaire 9 (PHQ-9)30 days post intervention

The Patient Health Questionnaire 9 (PHQ-9) consists of 10 questions with a total score ranging form 1 to 27, with a higher score indicating greater depression.

Emotional well-being as measured by the Generalized Anxiety Disorder 7-item (GAD-7) scale180 days post intervention

The Generalized Anxiety Disorder 7-item (GAD-7) scale has 7 questions each ranging in score from 0-3, with a higher score indicating a worse outcome.

Percentage of patients in the naive group that successfully taper off of the benzodiazepine or opioid90 days post intervention
Quality of life as measured by the Quality of life Score180 days post intervention

The range of scores is between 15 to 105, with a higher score or number being indicative of a higher quality of life.

Percentage of patients in the tolerant group that successfully taper off of the benzodiazepine or opioid180 days post intervention
Symptoms as measured by the Edmonton Symptom Assessment System (ESAS)30 days post intervention

The Edmonton Symptom Assessment System consists of 10 questions, each question ranging from 0-10, with a higher score indicating a worse outcome. The ESAS rates the intensity of common symptoms, including pain, tiredness, nausea, depression, anxiety, drowsiness, appetite, well-being, and shortness of breath.

Emotional well-being as measured by the Patient Health Questionnaire 9 (PHQ-9)180 days post intervention

The Patient Health Questionnaire 9 (PHQ-9) consists of 10 questions with a total score ranging form 1 to 27, with a higher score indicating greater depression.

Well-Being as measured by the Edmonton Symptom Assessment System (ESAS)180 days post intervention

The Edmonton Symptom Assessment System consists of 10 questions, each question ranging from 0-10, with a higher score indicating a worse outcome. The ESAS rates the intensity of common symptoms, including pain, tiredness, nausea, depression, anxiety, drowsiness, appetite, well-being, and shortness of breath.

Trial Locations

Locations (1)

The University of Texas Health Science Center at Houston

🇺🇸

Houston, Texas, United States

© Copyright 2025. All Rights Reserved by MedPath