Oral cleaning in intensive care unit patients with photodynamic therapy

Not Applicable

• Conditions: Ventilator-associated pneumonia due to bad oral hygiene (bacterial infection); C01.539.248.500; E05.318.308.250.300.675

• Registration Number: RBR-94bvrc
• Lead Sponsor: niversidade Nove de Julho

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-08
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Intensive care unit patient with 0 to 24h oro-tracheal intubation; patients whose family agree with the participation on this study and sign the agreement term; both genders, above 18 years old

Exclusion Criteria

Reintubation; readmission in Intensive Care Unit (ICU); smokers and ex-smokers for less than 5 years

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in oral bacteria amount in one intervention analysed by real-time PCR (polimerase chain reaction), comparing pre and post intervention samples

Secondary Outcome Measures

Name	Time	Method
Reduction in ventilator-associated pneumonia incidence in photodynamic therapy groups, doing daily the intervention and evaluating presence/absence of pneumonia after 5-8 days of treatment by analysis of medical cards