跳至主要内容
临床试验/CTRI/2025/02/081093
CTRI/2025/02/081093尚未招募不适用

Study to evaluate the short term outcomes of Comprehensive geriatric assessment in elderly patients undergoing surgical treatment of head and neck cancer

NIMS1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年3月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
NIMS
入组人数
100
试验地点
1
主要终点
Duration of hospital stay

研究概览

简要总结

Geriatric patients have a decreased physiological reserve to withstand aggressive surgical treatment. Frailty is a state of vulnerability to poor homeostasis post a stressor event such as chemotherapy or surgery. Handforth et al in their systematic review calculated the prevalence of frail and pre frail patients to be in the range of 40 – 45%. Identification of frailty in geriatric oncology patients helps in predicting their response to treatment, ability to tolerate major ablative procedures, recovery post treatment and even overall survival.

Elderly patients with good performance status have good outcomes to curative head and neck cancer patients, however they have longer hospital stays, tube dependence and non-fatal cardiac event. The rationale for the study is to identify at risk/ frail patients of head and neck cancer, predict and mitigate their complications and provide successful curative surgical intervention and post operative outcomes.

研究设计

研究类型
Observational

入排标准

年龄范围
60.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Age more than 60 years
  • Undergoing curative intent surgery of head and neck cancer.

排除标准

  • Not consenting for the study
  • Inability to perform TUG test ( 6 m walk test) or hand grip strength testing.

结局指标

主要结局

Duration of hospital stay

时间窗: At time of discharge (post surgery)

Calvin Dindo grade of complication

时间窗: At time of discharge (post surgery)

次要结局

  • Duration of ICU Stay(Ventilator requirement)

研究者

发起方
NIMS
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Abhilash Konkimalla

Nizams Institute of Medical Sciences

研究点 (1)

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