Comparative study of the therapeutic effects on periodontal disease using by antibiotics or probiotics
Not Applicable
- Conditions
- chronic periodontal disease
- Registration Number
- JPRN-UMIN000028545
- Lead Sponsor
- Fukuoka Dental College
- Brief Summary
All samples were obtained in a 3-month study of 10 patients (5 experimental, 5 control). Clinical symptoms of periodontal disease improved in all patients. As a result of the oral and intestinal bacterial flora analysis, it was found that there was a difference in the increase and decrease of bacterial species between the experimental group and the control group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
Minors, people who took antibiotics in the past 3 months, those with severe metabolic disorders (diabetes, liver disease, kidney disease) or malignant tumors, those with dairy allergy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Degree of periodontitis at 16 weeks after treatment start
- Secondary Outcome Measures
Name Time Method Bacterial composition of the oral cavity and the intestine