Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease (PNFS) Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Diseases
- Sponsor
- Zhejiang University
- Enrollment
- 2290
- Locations
- 2
- Primary Endpoint
- Numbers of participants with diabetes
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.
Detailed Description
Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.
Investigators
Yu Zhang
Professor
Zhejiang University
Eligibility Criteria
Inclusion Criteria
- •Subject aged ≥45 and ≤74 years old
- •Subject has complete data on diet and follow-up time
Exclusion Criteria
- •had the major illness that had made personal life disabled
Outcomes
Primary Outcomes
Numbers of participants with diabetes
Time Frame: From entry into the study baseline:2018 until 2023
Diabetes
Numbers of participants with metabolic syndrome
Time Frame: From entry into the study baseline:2018 until 2023
metabolic syndrome
Numbers of participants with obesity
Time Frame: From entry into the study baseline:2018 until 2023
Obesity
Secondary Outcomes
- Numbers of participants with cardiovascular diseases(From entry into the study baseline:2018 until 2023)
- Numbers of participants died(From entry into the study baseline:2018 until 2023)