Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease (PNFS) Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,290
- 试验地点
- 2
- 主要终点
- Numbers of participants with diabetes
研究概览
简要总结
The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.
详细描述
Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subject aged ≥45 and ≤74 years old
- •Subject has complete data on diet and follow-up time
排除标准
- •had the major illness that had made personal life disabled
结局指标
主要结局
Numbers of participants with diabetes
时间窗: From entry into the study baseline:2018 until 2023
Diabetes
Numbers of participants with metabolic syndrome
时间窗: From entry into the study baseline:2018 until 2023
metabolic syndrome
Numbers of participants with obesity
时间窗: From entry into the study baseline:2018 until 2023
Obesity
次要结局
- Numbers of participants with cardiovascular diseases(From entry into the study baseline:2018 until 2023)
- Numbers of participants died(From entry into the study baseline:2018 until 2023)
研究者
Yu Zhang
Professor
Zhejiang University