Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease Study

Active, not recruiting

• Conditions: Chronic Diseases

• Registration Number: NCT05247632
• Lead Sponsor: Zhejiang University

Brief Summary

The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.

Detailed Description

Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.

Study Timeline

• Study Start: 2018-05-01
• Study First Submitted: 2022-02-03
• Study First Submitted QC: 2022-02-09
• Study First Posted: 2022-02-21
• Status Verified: 2023-03
• Last Update Submitted: 2024-01-07
• Last Update Posted: 2024-01-10
• Primary Completion: 2024-05-01
• Study Completion: 2028-07-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 2290

Inclusion Criteria

• Subject aged ≥45 and ≤74 years old
• Subject has complete data on diet and follow-up time

Exclusion Criteria

had the major illness that had made personal life disabled

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Numbers of participants with diabetes	From entry into the study baseline:2018 until 2023	Diabetes
Numbers of participants with metabolic syndrome	From entry into the study baseline:2018 until 2023	metabolic syndrome
Numbers of participants with obesity	From entry into the study baseline:2018 until 2023	Obesity

Secondary Outcome Measures

Name	Time	Method
Numbers of participants with cardiovascular diseases	From entry into the study baseline:2018 until 2023	Cardiovascular diseases
Numbers of participants died	From entry into the study baseline:2018 until 2023	All-cause and cause-specific mortality

Trial Locations

Locations (2)

Lanxi Red Cross Hospital; 🇨🇳 Lanxi, Zhejiang, China

Lanxi Hospital of Traditional Chinese Medicine; 🇨🇳 Jinhua, China