Establishment of Image Database for Early Upper Gastrointestinal Cancer, Precancerous Lesions, and Precancerous Conditions
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, and CT images
研究概览
简要总结
The study is designed to collect magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, CT images, and histopathology results to establish a database for early upper gastrointestinal cancer, precancerous lesions, and precancerous conditions.
详细描述
Images of MCE for UGIC are scarce, limiting the development of corresponding AI diagnostic model. We aim to create an image database with MCE images, EGD images, CT images, and histopathology results, in patients treated by ESD for early upper gastrointestinal cancer, or biopsy for precancerous lesions, and precancerous conditions, so as to facilitate image-based deep learning studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female participants aged ≥ 18 years
- •Patients with early upper gastrointestinal cancer referred for endoscopic submucosal dissection (ESD), or patients with upper gastrointestinal precancerous lesions or precancerous conditions referred for biopsy by esophagogastroduodenoscopy (EGD)
- •Participants who are willing and able to participate in this study, complete all required examinations and follow-up visits, and who have provided written informed consent
排除标准
- •Patients who are not eligible for surgery or who refuse any abdominal surgery in case of capsule retention and endoscopic retrieval failure
- •Patients with cardiac pacemaker or other implanted electromedical devices which could interfere with magnetic resonance
- •Suspected or known intestinal stenosis or other known risk factors for capsule retention
- •Patients with dysphagia
- •Allergy to polymeric materials, latex, simethicone, or pronase
- •Patients plan to undergo magnetic resonance imaging examination before excretion of the capsule
- •Patients with any condition that precludes compliance with the study
结局指标
主要结局
Magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, and CT images
时间窗: Prior to ESD or biopsy
Histopathology results
时间窗: During ESD or biopsy
次要结局
未报告次要终点
研究者
Jun Pan
Principal Investigator
Changhai Hospital