Hypnosis for Chronic Idiopathic Pruritus

Not Applicable

Completed

• Conditions: Chronic Idiopathic Pruritus
• Interventions: Other: Hypnosis

• Registration Number: NCT04829578
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, for which there is no specific treatment. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Detailed Description

Chronic idiopathic pruritus (CIP) is a frequent and disabling condition, with significative impact on quality of life. At present, there is no specific treatment for CIP. Topical steroids are frequently used, with partial efficacy, and adverse effects. Hypnosis is a specific state of conscience. It differs from waking state, sleeping state, relaxation, or meditation. In this state, the person is highly responsive to suggestion. In medicine, hypnosis can be used to engage the internal resources of the person against unpleasant feelings. It was shown previously that hypnosis can relieve painful sensations. Pain and pruritus share many similarities regarding sensory receptors and pathways, suggesting that hypnosis might help relief CIP.

Study Timeline

• Study First Submitted: 2021-03-26
• Study First Submitted QC: 2021-03-31
• Study First Posted: 2021-04-02
• Study Start: 2021-04-13
• Primary Completion: 2021-09-13
• Study Completion: 2022-10-31
• Status Verified: 2024-01
• Last Update Submitted: 2024-01-11
• Last Update Posted: 2024-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Male or female of at least 18 years at screening
• Diagnosis of chronic (at least 6 wks.) idiopathic pruritus
• Pruritus Numeric Rating Scale > = 4

Exclusion Criteria

• Pruritus caused by a dermatological or a systemic conditions
• Suicidal crisis, moderate, or severe
• Psychosis (schizophrenia, persistent delusional disorder)
• Bipolar disorder, not stabilized or decompensating
• Personality disorder, decompensated

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Hypnosis	Hypnosis	hyspnosis treatment

Primary Outcome Measures

Name	Time	Method
Change From Baseline in Pruritus Numeric Rating Scale	Day 84	Assessment of the intensity of pruritis in Pruritus Numeric Rating Scal; the minimum and maximum values 0 to 10

Secondary Outcome Measures

Name	Time	Method
Change From Baseline in Pruritus Verbal Rating Scale	Day 84	Assessment of Pruritus by pruritus Verbal Rating Scale; the minimum and maximum values 0 to 4
Change From Baseline in DLQI scale	Day 84	assessment in DLQI scale; result between 0 to 30
Change From Baseline in HAD scale	Day 84	assessment in HAD scale; result between 0 to 42
Change From Baseline in usage of topical steroids	Day 84	assessment in usage of topical steroids
Change From Baseline in Sleeping Scale	Day 84	assessment in sleeping scale ; the minimum and maximum values 0 to 10
Evaluation of tolerance of hypnosis	Day 84	assessment of tolerance of hypnosis with report of adverse event

Trial Locations

Locations (1)

Chu de Nice; 🇫🇷 Nice, France