EUCTR2008-006161-84-GB进行中（未招募）不适用
ARTiST - Aromasin Randomised Trial +/- Sutent as neoadjuvant Therapy for post-menopausal women with breast cancer. - ARTiST
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Female
入选标准
- •Key Inclusion criteria
- •-Ultrasound Size: greater than 1 cm.
- •-Diagnosis of invasive breast cancer on core biopsy.
- •-Patients with localised or locally advanced invasive breast cancer.
- •-Histological grade : G1-3.
- •-ER positive (Allred = 4).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Previous history of cancer, excluding basal cell carcinoma or cervical carcinoma in-situ.
- •- Previous deep vein thrombosis or pulmonary embolism.
- •- Uncontrolled hypertension.
- •-Any of the following within the 12 months prior to study drug administration: myocardial infarction, severe/unstable angina, coronary/peripheral artery bypass graft, symptomatic congestive heart failure, cerebrovascular accident or transient ischemic attack.
- •-Pre-existing thyroid abnormality with thyroid function that cannot be maintained in the normal range with medication.
- •-Ongoing cardiac dysrhythmias of = grade 2 (NCI CTCAE grading version 3.0), atrial fibrillation of any grade, or prolongation of the QTc interval >470 msec.
- •-Treatment with terfenadine, quinidine, procainamide, disopyramide, sotalol, probucol, bepridil, haloperidol, risperidone, ketoconazole or indapamide
- •- Known human immunodeficiency virus (HIV) positive, or acquired immunodeficiency syndrome (AIDS) related illness.
- •- Osteoporosis
研究者
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