Clinicopathologic Significance of Splenomegally in Adult Patients With Isolated Thrombocytopenia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 主要终点
- Investigate prevalence of splenomegally in patients with isolated thrombocytopenia. Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome
研究概览
简要总结
Investigate prevalence of splenomegally in patients with isolated thrombocytopenia.
Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome To explain possible causes of splenomegally in patients with isolated thrombocytopenia
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients more than 18 years admitted with isolated thrombocytopenia due to primary Immune thrombocytopenic purpura amegakaryocytic aplasia Unilineage myelodysplastic syndrome ( megakaryocyte dysplasia) lymphoproliferative disorder with secondary ITP autoimmune diseases with secondary ITP Willingness to participate in the study Admitted patients or those who follow at hematology outpatients clinic
排除标准
- •EDTA induced pseudothrombocytopenia Platelet satellitism Drug induced thrombocytopenia Heparin induced thrombocytopenia / thrombosis syndrome post transfusion purpura Disseminated intravascular coagulopathy patients less than 18 years old patients with bicytopenia or pancytopenia Pregnancy
结局指标
主要结局
Investigate prevalence of splenomegally in patients with isolated thrombocytopenia. Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome
时间窗: Baseline
1. How many patients with isolated thrombocytopenia present with splenomegaly 2. Do patients with splenomegaly experience different complications compared to those without splenic enlargement 3. Is there a difference in treatment response between patients presenting with splenomegaly and those without splenic involvement
次要结局
未报告次要终点
研究者
Karim Ashraf hussein youssef
Resident in Internal Medicine Department in Assiut University Hospitals
Assiut University