Analgesic Effect to Postoperative Pain After Mastectomy: Ultrasound-guided Serratus Anterior Plane Block

Not Applicable

Completed

• Conditions: Breast Cancer
• Interventions: Drug: Ultrasound guided serratus anterior block with ropivacaine; Drug: intravenous PCA only

• Registration Number: NCT02483923
• Lead Sponsor: Yonsei University

Brief Summary

Ultrasound guided serratus anterior plane block may decrease acute postoperative pain and consumption of opioid after mastectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-06-16
• Study First Submitted: 2015-06-18
• Study First Submitted QC: 2015-06-24
• Study First Posted: 2015-06-29
• Primary Completion: 2016-02-28
• Study Completion: 2016-02-28
• Status Verified: 2018-07
• Last Update Submitted: 2018-07-15
• Last Update Posted: 2018-07-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. ASA 1~3
2. Age 20~80
3. Breast cancer patient twho are scheduled for elective mastectomy

Read More

Exclusion Criteria

1. Allergy to local anesthetics or contraindication to use of ropivacaine
2. Pregnancy
3. Severe cardiovascular disease
4. Renal failure
5. Liver failure
6. Neurologic and psychologic disease
7. Chronic treatment with analgesics
8. Previous history of mastectomy or thoracic surgery.

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group S	Ultrasound guided serratus anterior block with ropivacaine	-
Group C	intravenous PCA only	-

Primary Outcome Measures

Name	Time	Method
Total opioid consumption	within 24 hrs after mastectomy	Assessing total opioid consumption (total number of bolus injection and total dose of fentanyl via intravenous patient controlled analgesia) within 24hours after operation finished.

Secondary Outcome Measures

Name	Time	Method
Postoperative pain scale (Numeric rating scale 0-10) at PACU	chang from 3,6,12,24 to 48hrs after operation end
Total intraoperative remifentanil consumption(mcg)	within 24 hrs after mastectomy
Additional analgesics requirements (dose/number)	within 24 hrs after mastectomy
incidence and intensity of postoperative nausea and vomiting(NRS:0-10)	within 24 hrs after mastectomy
Total hospital staying time	within 24 hrs after mastectomy

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of