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Clinical Trials/NCT04278807
NCT04278807
Completed
Not Applicable

Analgesic Efficacy of PENG Block Compared to FIB Block in the Elderly Patient With Fracture of the Proximal Femur in the Emergency Room

Santo Spirito Hospital, Italy1 site in 1 country60 target enrollmentFebruary 14, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain Relief in Proximal Femoral Fracture
Sponsor
Santo Spirito Hospital, Italy
Enrollment
60
Locations
1
Primary Endpoint
Evaluation of success rate of PENG block (defined as NRS score </ = 4 at 30 minutes from the blockade placement by comparing it to the analgesic effect of the FIB block, also evaluated at 30 minutes as NRS score </ = 4).
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The trial aims to verify a possible greater analgesic efficacy of PENG (Pericapsular Nerve Group) block compared to iliac fascia block (FIB block) in elderly patients (age > 65 years) suffering from traumatic fracture of proximal femur in emergency room.

Detailed Description

Prospective randomized double-blind single-center preliminary study aimed to demonstrate a possible greater analgesic efficacy of the PENG block compared to the iliac fascia block (FIB block) in elderly patients (age \> 65 years) suffering from traumatic fracture of the proximal femur in emergency room. The study will cover patients aged \> 65 years suffering from a proximal traumatic fracture of the femur who access the emergency room of Santo Spirito Hospital in Rome (ASL Roma 1).

Registry
clinicaltrials.gov
Start Date
February 14, 2020
End Date
September 19, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Santo Spirito Hospital, Italy
Responsible Party
Principal Investigator
Principal Investigator

Dr Francesco Marrone

Principal Investigator

Santo Spirito Hospital, Italy

Eligibility Criteria

Inclusion Criteria

  • all patients \> 65 years suffering from a proximal traumatic fracture of a femur who access the emergency room of Santo Spirito Hospital in Rome (ASL Rome 1), for whom surgical treatment of osteosynthesis is recommended within 48 hours in accordance with the guidelines of Regional Health System (Regione Lazio).

Exclusion Criteria

  • Failure to acquire written and valid informed consent
  • Obesity (BMI\> 35 kg / m2)
  • Contraindications to performing regional anesthesia (severe coagulopathies and / or thrombocytopenia, septic state and / or infections at the block site, allergy to local anesthetics)
  • Patients on therapy with antiplatelet agents, anticoagulants or who regularly use opioids, NSAIDs, acetaminophen for chronic painful conditions;
  • History of alcohol or drug abuse;
  • Severe kidney or liver failure;
  • Cognitive alterations, dementia, psychiatric pathologies

Outcomes

Primary Outcomes

Evaluation of success rate of PENG block (defined as NRS score </ = 4 at 30 minutes from the blockade placement by comparing it to the analgesic effect of the FIB block, also evaluated at 30 minutes as NRS score </ = 4).

Time Frame: 30 minutes after the placement of nerve block

Numeric Rating Scale (NRS-score) evaluation, from 0 (no pain) to 10 (worst pain).

Secondary Outcomes

  • Evaluation of rest and incident pain(30 minutes after the placement of nerve block)
  • Check for any complications related to analgesic (PENG and FIB) blocks(from 30 minutes to 12 hours)
  • Onset time and duration of nerve blockade(from 30 minutes to 12 hours)
  • Use of rescue-medication in pain treatment(from 30 minutes to 12 hours)

Study Sites (1)

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