Efficasy of cinnarizine in the prophylaxis of migraine headache
- Conditions
- migraine.migraine
- Registration Number
- IRCT201107216907N2
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 68
1. Patients with migraine (with or without aura), diagnosed according to the International Headache society criteria. 2. Patients who had one or more migraine attack per week ; or sever dysfunction in daily and school activities during prospective baseline phase. 3. Headaches must not relate to any known structural brain lesion or other systemic conditions. Exclusion criteria: 1. Chronic headache, complications of migraine or other migraine variant. 2. Children and adolescents with Focal neurologic deficit. 3. History of diagnosed sensitivity to cinnarizine . 4. Patients who showed sever adverse effect to the study treatment drugs (in the double-blind phase of the study). 5. Serious comorbidities (hepatic, renal, cardiovascular or thyroid disease). 6. Patients who took prophylactic therapy for migraine within 4 weeks before study.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of headache. Timepoint: monthly. Method of measurement: questionnaire.;Severity of headache. Timepoint: monthly. Method of measurement: questionnaire( VAS).;Duration of attack. Timepoint: monthly. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method Adverse effects of cinnarizine. Timepoint: each time during the study. Method of measurement: ask from participants and parents.