Ventilation oxygen support for COPD
- Conditions
- exertional hypoxemic COPD
- Registration Number
- NL-OMON29565
- Lead Sponsor
- Philips Group Innovation - Research, High Tech Campus 34 5656 AE Eindhoven, The Netherlands
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 13
Inclusion Criteria
Subjects eligible for participation should meet the following criteria:
Exclusion Criteria
Exclusion criteria for subject selection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of the present study is to investigate whether or not patients with COPD with normal blood gases and static hyperinflation at rest, but hemoglobin oxygen desaturation during exercise have beneficial effects of continuous or intermittent oxygen therapy combined with bilevel positive pressure non-invasive ventilation, in terms of time to recovery after exercise and duration of continuation of exercise after recovery. <br>
- Secondary Outcome Measures
Name Time Method Secondary objective of the study is to compare the intermittent use of oxygen and bilevel positive pressure non-invasive ventilation to continuous use, in terms of time to recovery after exercise and duration of continuation of exercise after recovery <br /><br>Additional secondary objectives of the study are to investigate whether or not the interventions described in the primary objective have beneficial effects on heart rate, heart rate recovery, exercise induced oxygen desaturation, exercise induced changes in transcutaneous measured pCO2, changes in breathing frequency, dynamic hyperinflation, dyspnea scores, leg discomfort. <br>