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临床试验/NCT01057368
NCT01057368已完成不适用

The Effects of Well-being Interventions on Affect, Attention, Sleep, Social Stress and Pain Regulation

University of Wisconsin, Madison3 个研究点 分布在 1 个国家目标入组 161 人开始时间: 2009年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
161
试验地点
3
主要终点
Salivary Cortisol

研究概览

简要总结

This study is focused on the brain mechanisms and peripheral biological correlates of two different forms of meditation--mindfulness-based and compassion/loving-kindness. Project 1 is focused on the impact of compassion/loving-kindness meditation on emotional reactivity and emotion regulation. Project 2 is focused on the neural and behavioral correlates of mindfulness meditation and attention and pain regulation. In addition, Project 2 will examine the relations between changes in oscillatory rhythms during meditation and attention and pain processing. Project 3 will examine the impact of meditation on spontaneous brain activity during sleep. This project will also examine the impact of intensive meditation on regional changes in slow wave activity during subsequent sleep. Each of these projects will be conducted on the same participants so that interrelations among the various measures collected in the different projects can be examined. We believe that this study will dramatically advance the understanding of the mechanisms by which meditation produces changes in behavioral and biological processes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Basic Science
盲法
Single (Investigator)

入排标准

年龄范围
25 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • 未提供

排除标准

  • •Not available for scheduled visits or applicable interventions
  • •Current medical conditions that may affect outcome measures, including chronic inflammatory diseases, asthma, serious mental health diagnoses, chronic pain conditions, a personal history of seizures
  • •Regularly taking medications that may affect outcome measures, including pain medications, corticosteroids, immuno-suppressants, prescription sleep medications, psychotropic medications
  • •Alcohol or non-prescription drug problems
  • •Night-shift worker
  • •Diagnosed sleep disorder or habits, such as late bedtime, that would prevent enough sleep in the laboratory
  • •Previous training related to one of the two active interventions for meditation naive participants
  • •Unwillingness or inability to engage in intervention activities as determined by participant or their primary care physician
  • •Currently pregnant or planning on becoming pregnant in the next year
  • •Currently nursing
  • •Current IUD

研究组 & 干预措施

Wait List Controls

No Intervention

Long Term Meditators

Active Comparator

干预措施: Day of intensive meditation practice (Behavioral)

Mindfulness Based Stress Reduction

Active Comparator

干预措施: Mindfulness Based Stress Reduction (MBSR) (Behavioral)

Health Enhancement Program

Active Comparator

干预措施: Health Enhancement Program (HEP) (Behavioral)

结局指标

主要结局

Salivary Cortisol

时间窗: Pre, post, & follow-up (WL & LTP)

EEG

时间窗: Pre, post, & follow-up (WL & LTP)

Behavioral

时间窗: Pre, post, & follow-up (WL & LTP)

Self-report

时间窗: Pre, post, & follow-up (WL & LTP)

MRI BOLD

时间窗: Pre, Post, Follow-up (WL & LTP)

次要结局

  • Self-report(Pre, post, & follow-up (WL & LTP))

研究者

申办方类型
Other
责任方
Sponsor

研究点 (3)

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