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Clinical Trials/ISRCTN16139487
ISRCTN16139487
Completed
Not Applicable

Autologous bone marrow stem cell transplantation in patients with decompensated liver cirrhosis: results from first in man study

. Kipshidze Central University Hospital (Georgia)0 sites34 target enrollmentApril 15, 2015
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ConditionsDecompensated liver cirrhosisDigestive SystemChronic Liver Disease/Cirrhosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Decompensated liver cirrhosis
Sponsor
. Kipshidze Central University Hospital (Georgia)
Enrollment
34
Status
Completed
Last Updated
10 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 15, 2015
End Date
TBD
Last Updated
10 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
. Kipshidze Central University Hospital (Georgia)

Eligibility Criteria

Inclusion Criteria

  • •1\. Chronic hepatic failure
  • •2\. Ultrasonographic evidences of cirrhosis and portal hypertension
  • •3\. Child\-Pough class B and C score
  • •4\. Patients must have the ability to sign the informed consent

Exclusion Criteria

  • •1\. Patients aged less than 18 or more than 70
  • •2\. Hepatopulmonary syndrome
  • •3\. Documented hepatocellular carcinoma or history of other cancer
  • •4\. Presence of hepatic, portal or splenic vein thrombosis on doppler ultrasonography
  • •5\. History of autoimmune diseases
  • •6\. Use of hepatotoxic drugs within the last 6 month before enrolment
  • •7\. Decompensated heart failure
  • •8\. Renal failure (creatinine \>2\.5 mg/dL)
  • •9\. International normalized ratio (INR) \>2\.2
  • •10\. Patients with acute infection

Outcomes

Primary Outcomes

Not specified

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